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Cancer blog from medicineworld.org  
Released:  4/12/2009 6:49:26 AM
RSS Link:  http://medicineworld.org/stories/rss/cancer-blog.xml
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Cancer blog from medicineworld.org adds a personal touch to the stories related to cancer. This cancer blog brings you stories of hope, stories of survivors and latest news and research related to cancer.


Contents:

New chemotherapy combination for endometrial cancer
Scientists from The University of Texas M. D. Anderson Cancer Center report that in a small study of women with advanced or recurrent endometrial cancer, gemcitabine and cisplatin, when used in combination, produced a response rate in fifty percent of patients. Jubilee Brown, M.D., associate professor in M. D. Anderson's Department of Gynecologic Oncology, presented the findings at today's plenary session of the Society of Gynecologic Oncologists' 41st Annual Meeting on Women's Cancer........


How cancer and obesity are linked
The link between obesity and disease has been well documented. There's evidence now that obesity and cancer have a strong link, as they've shown in the United States at least 90,000 cancer deaths a year can be attributed to obesity. University of Alberta researcher Richard Lamb is on his way to understanding the correlation and it's a good example of how the scientific process works........


Preventing gastric cancer with antibiotics
Helicobacter pylori, a bacterium found in about 50% of humans worldwide, can cause stomach ulcers and, in extreme cases, gastric cancer. In an article for F1000 Medicine Reports, Seiji Shiota and Yoshio Yamaoka discuss the possible eradication of H. pylori infections. Infection by the H. pylori bacterium can approach 100% in developing countries. Most infected people do not have symptoms, but a number of develop problems including stomach ulcers. H. pylori causes more than 90% of all duodenal ulcers and can also contribute to the development of gastric cancer, which is one of the world's biggest medical problems........


Papaya extract against cancer
The humble papaya is gaining credibility in Western medicine for anticancer powers that folk cultures have recognized for generations. University of Florida researcher Nam Dang, M.D., Ph.D., and his colleagues in Japan have documented papaya's dramatic anticancer effect against a broad range of lab-grown tumors, including cancers of the cervix, breast, liver, lung and pancreas. The scientists used an extract made from dried papaya leaves, and the anticancer effects were stronger when cells received larger doses of the tea........


Key cause of chronic leukemia progression
COLUMBUS, Ohio Scientists have discovered a key reason why a form of leukemia progresses from its more-treatable chronic phase to a life-threatening phase called blast crisis. The study, led by cancer scientists at the Ohio State University Comprehensive Cancer Center-Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC-James), indicates that chronic myeloid leukemia (CML) progresses when immature white blood cells lose a molecule called miR-328........


Genetic link between mammographic density and breast cancer
A University of Melbourne study has revealed that certain breast cancer genetic variants increase mammographic density, confirming the link between mammographic breast density and breast cancer. Professor John Hopper of the University's School of Population Health says women vary greatly in their underlying risk of breast cancer. "These findings provide an insight into possible new pathways into the development of breast cancer"........


Key interaction that controls telomeres
In the dominoes that make up human cells, scientists at the University of Michigan Comprehensive Cancer Center have traced another step of the process that stops cells from becoming malignant. It starts with the enzyme telomerase, which affects the caps, or telomeres, at the end of a chromosome. Telomeres shorten over time. But telomerase prevents this from happening, making the cell immortal. If cancer is triggered in the cell, the presence of telomerase leads to the growth of the cancer........


Killing cancer with nano
Using lasers and nanoparticles, researchers at Rice University have discovered a new technique for singling out individual diseased cells and destroying them with tiny explosions. The researchers used lasers to make "nanobubbles" by zapping gold nanoparticles inside cells. In tests on cancer cells, they found they could tune the lasers to create either small, bright bubbles that were visible but harmless or large bubbles that burst the cells........


Barriers to screening for colorectal cancer
Colorectal cancer is the second leading cause of cancer-related deaths in the United States. Despite evidence and guidelines supporting the value of screening for this disease, rates of screening for colorectal cancer are consistently lower than those for other types of cancer, particularly breast and cervical. Although the screening rates in the target population of adults over age 50, have increased from 20-30 percent in 1997 to nearly 55 percent in 2008 the rates are still too low. An NIH state-of-the-science panel was convened this week to identify ways to further increase the use and quality of colorectal cancer screening in the United States........


Plant derivative may fight cancer
Medical College of Georgia scientists are seeking to refine cancer therapy with an anti-inflammatory plant derivative long used in Chinese medicine. Celastrol, derived from trees and shrubs called celastracaea, has been used for centuries in China to treat symptoms such as fever, chills, joint pain and inflammation. The MCG scientists think it may also play a role in cancer therapy by inactivating a protein mandatory for cancer growth........


Curing More Cervical Cancer Patients
Cervical cancer is highly curable when caught early. But in a third of cases, the tumor responds poorly to treatment or recurs later, when cure is much less likely. Quicker identification of non-responding tumors appears to be possible using a new mathematical model developed by scientists at the Ohio State University Comprehensive Cancer Center-Arthur G. James Cancer Hospital and Richard J. Solove Research Institute........


Approval of oncology drugs at FDA
Over a two and half year period, beginning in 2005 when the U.S. Food and Drug Administration's oncology drug product's office began reviewing marketing applications, a total of 60 new oncology and hematology drugs were evaluated, of which 53 were approved, as per a new article published online January 29 in the Journal of the National Cancer Institute.......


New computational tool for cancer treatment
A number of human tumors express indoleamine 2,3-dioxygenase (IDO), an enzyme which mediates an immune-escape in several cancer types. Scientists in the Molecular Modeling group at the SIB Swiss Institute of Bioinformatics and Dr. Benot J. Van den Eynde's group at the Ludwig Institute for Cancer Research Ltd (LICR) Brussels Branch developed an approach for creating new IDO inhibitors by computer-assisted structure-based drug design. The study was presented in the January 2010 online issue of the Journal of Medicinal Chemistry.......


How pancreatic cancer able to defeat drugs
Scientists at the Moores Cancer Center at the University of California, San Diego, have found one reason that pancreas cancer tumors are so difficult to treat with drugs. They have shown how a molecular switch steps up pancreas cancer cell survival as well as resistance to a standard chemotherapy drug, and have identified alternate routes cancer cells take to avoid the effects of the treatment........


Change in mammography guidelines
The methodology and evidence behind a widely publicized change in national mammography guidelines is questionable, as per a review in the Journal of Diagnostic Medical Sonography (JDMS), published by SAGE. In November 2009, the US Preventive Services Task Force (USPSTF) published a report in the Annals of Internal Medicine discussing the screening techniques for the early detection of breast cancer. A few isolated portions of that report, regarding recommended changes for the use of mammography, were widely discussed in the media, and garnered tremendous public attention........


Virtual colonoscopy is effective
Computed tomographic colonography (CTC), also known as virtual colonoscopy, remains effective in screening older patients for colorectal cancer (CRC), produces low referral for colonoscopy rates similar to other screening exams now covered by Medicare, and does not result in unreasonable levels of additional testing resulting from extracolonic findings, as per a research studyreported in the recent issue of Radiology........


Lung cancer patients who quit smoking
People diagnosed with early stage lung cancer can double their chances of survival over five years if they stop smoking compared with those who continue to smoke, finds a study published on bmj.com today. This is the first review of studies to measure the effects of continued smoking after diagnosis of lung cancer and suggests that it appears to be worthwhile to offer smoking cessation therapy to patients with early stage lung cancer........


Who's afraid of the HPV vaccine?
A newly released study concludes that people tend to match their risk perceptions about policy issues with their cultural values, which may explain the intense disagreement about proposals to vaccinate elementary-school girls against human-papillomavirus (HPV). The study also says people's values shape their perceptions of expert opinion on the vaccine........






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